The 'Sesbian Lex' meme is a popular spoonerism of 'Lesbian Sex' that gained significant traction within online fandoms, particularly those centered around anime and video games like Signalis and Genshin Impact. The term is typically used to jokingly describe the intense romantic tension between two female characters or to celebrate 'yuri' ships. Emerging as a common typo or intentional misspelling on platforms like Twitter and Reddit, it has evolved into a catch-all reaction phrase. Fans often overlay the text on screenshots where characters are simply standing near each other, satirizing how quickly shippers jump to conclusions while simultaneously embracing the queer representation.