The Saint Young Men meme stems from the popular slice-of-life manga and anime series Saint Oniisan, which features Jesus Christ and Gautama Buddha living as roommates in a low-rent apartment in Tokyo. The humor arises from their attempts to hide their divine identities while experiencing mundane human activities like grocery shopping, using social media, and navigating public transport. The meme templates usually highlight their contrasting personalities—Jesus being the impulsive, trendy shopper and Buddha being the calm, frugal one. It is widely used to depict unlikely friendships, relatable roommate struggles, or to add a spiritual twist to everyday scenarios through the lens of divine characters being surprisingly down-to-earth.