The Resident Evil 2 Remake meme often centers on the relentless pursuit of Mr. X, the intimidating Tyrant sent to eliminate survivors in the Raccoon City Police Department. Since the game's release in 2019, players have turned the survival horror atmosphere into comedy by labeling Mr. X as inescapable real-life problems or adding humorous soundtracks to his heavy footsteps. These memes perfectly capture the sensation of being chased by an unstoppable force, using Leon S. Kennedy or Claire Redfield as proxies for the stressed-out user. It has become a staple for describing anxiety, impending deadlines, or any looming threat that refuses to let up.