The 1987 comedy classic 'Planes, Trains and Automobiles' features one of the most iconic comedic meltdowns in cinema history. Steve Martin, playing the high-strung Neal Page, finally reaches his breaking point with the well-meaning but incredibly annoying Del Griffith, played by John Candy. In this specific scene, Neal unleashes a verbal barrage, punctuated by the blunt question 'What is your problem?' and the scathing label 'insensitive asshole.' It is a masterclass in controlled fury, capturing the exact moment when politeness evaporates in the face of sheer incompetence. Today, this clip is the gold standard for reaction memes used to vent frustration toward oblivious or inconsiderate people. It represents the relatable feeling of being trapped in a situation with someone who lacks total self-awareness, whether in an office, on public transit, or within a family dynamic. Meme creators use this to signal that a boundary has been crossed and patience has run out. Example caption ideas: 'When the coworker who does nothing starts giving you advice,' 'Me watching someone talk through the entire movie,' and 'When your friend suggests another 8 AM hike on a Saturday.'