The 'Once in a Lifetime' meme originates from the 1980 music video by the New Wave band Talking Heads, featuring lead singer David Byrne's erratic and iconic dancing. Clad in a large suit and sporting a bewildered expression, Byrne recites lyrics that capture existential confusion, such as 'How did I get here?' and 'This is not my beautiful house.' The meme gained longevity due to its surreal visual style and its ability to represent moments of sudden realization, mid-life crises, or the repetitive nature of daily existence. It is widely used on social media to highlight absurd situations where someone feels completely out of place or stuck in a loop.