The Niña 'Osea, Que Pedo' meme features a young Mia Talerico as Charlie Duncan from the Disney Channel sitcom 'Good Luck Charlie.' The image captures a scene from the 2011 episode 'Meet the Parents,' where Charlie makes a signature puzzled face and gestures with her hands up. While the English-speaking world often uses it to represent an 'I don't know' or 'Why?' reaction, it became a massive viral sensation in Latin America, where it was dubbed the 'Osea, ¿Qué Pedo?' girl. It is widely used to express bewilderment, sarcasm, or reaction to a situation that makes absolutely no sense.