The 'My Son He Has Every Disease' meme originated from a viral Tumblr thread featuring a low-resolution, distorted image of a creature (often a cat or a Pokemon). The absurd, overly dramatic caption quickly became a staple of surreal internet humor and shitposting culture. It is typically used to describe something that looks physically glitchy, pathetic, or 'cursed' in an endearing yet bizarre way. Over time, the phrase has been applied to various characters and pets, serving as a go-to reaction for anything that looks hilariously unwell or poorly rendered.