The 'Karma Is a Bitch' meme gained massive popularity through various internet challenges, most notably the TikTok 'glow-up' trend where users transformed from their everyday look to a high-fashion aesthetic. Often associated with a dramatic line from the show Riverdale, the meme evolved into a broader cultural shorthand for poetic justice. It is frequently used to depict situations where someone's overconfidence is met with a harsh reality check or an unexpected reversal of fortune. Whether used for personal transformations or witnessing someone's comeuppance, the template remains a go-to for expressing the satisfying sting of cosmic retribution.