The 'Is Four A Lot' meme stems from a dialogue in the Doctor Who episode 'Deep Breath.' The Twelfth Doctor asks Clara Oswald if the number four is significant, leading to her iconic response: 'Depends on the context. Pennies? No. Murders? Yes.' This exchange perfectly captures the concept of relativity, and the internet quickly adopted it as a multi-panel template. It is frequently used to compare trivial quantities with extreme or unexpected situations, making it a staple for educational, political, and relatable humor across social media platforms like Reddit and Tumblr.