The 'I Miss My Wife, Tails' meme originates from the 2018 'Sonic Adventure 2 Real-Time Fandub' produced by the YouTube channel SnapCube. During a sequence where the voice actors were improvising over the game's cutscenes, Alfred Coleman (voicing Dr. Eggman) delivered a bizarrely emotional and nonsensical monologue about his missing wife before abruptly leaving the scene. The absurdity of Eggman having a wife, combined with the deadpan delivery in such a chaotic context, turned the quote into an immediate viral sensation. It is commonly used as a reaction image or caption to express mock grief, existential dread, or simply to reference the wider 'Eggman's Announcement' series of memes from the same fandub.