GrandmaBetty33, known in real life as Betty Simpson, became an internet icon for her courageous and joyful documentation of her battle with cancer. Starting in 2014, her great-grandson set up an Instagram account to share her daily life, which quickly amassed millions of followers who were touched by her resilience and signature blue tongue from her favorite candies. Even after her passing, her image remains a symbol of pure positivity and the importance of living life to the fullest regardless of the circumstances. In the meme world, her template is primarily used for wholesome content, celebrating small wins, and spreading genuine happiness across social media platforms.