The 'Gossip Girl Title Remix' meme, famously known as 'Go Piss Girl,' emerged in early 2020 as a creative wordplay trend on Twitter. It utilizes a two-panel format featuring Serena van der Woodsen and Blair Waldorf from the original TV series intro. By rearranging or photoshopping the letters of the 'Gossip Girl' show title, users create absurd and often nonsensical phrases that the characters appear to be saying to each other. The trend's humor stems from the contrast between the show’s high-fashion, high-drama aesthetic and the juvenile or bizarre nature of the remixed text, turning a glamorous CW promo into a versatile template for internet absurdity.