The 'Give Me One Margarita' meme exploded onto the scene in mid-2023, originating from a viral freestyle by comedian and actress Angel Laketa Moore, known as That Chick Angel. The lyrics were a comedic response to a video of a street preacher claiming that alcohol leads to promiscuity. Moore flipped the script with a catchy, escalating rhyme about what she would do after one, two, three, four, and five margaritas. The song was eventually turned into a full-length track produced by Casa Di and Steve Terrell, becoming a massive summer anthem. The meme is frequently used to accompany funny dances, party footage, or relatable situations involving cocktails and a lack of impulse control.