The Girugamesh meme originated from a promotional commercial for Sakura-Con 2009, featuring a highly enthusiastic fan wearing a Girugamesh band shirt who shouts the band's name with sudden, intense energy. The clip quickly became a viral sensation on YouTube and image boards due to the fan's unexpected passion and the catchy, rhythmic delivery of the name. It is typically used as a reaction to express extreme excitement, sudden outbursts, or as a nostalgic nod to early 2010s anime convention culture. The meme remains a staple of internet history, often edited into remixes or used to punctuate moments of high-octane energy in videos.