The Ghostbusters meme is rooted in the legendary 1984 supernatural comedy film and its iconic theme song by Ray Parker Jr. The 'Who you gonna call?' catchphrase has transcended the movie to become a universal response to any problem, supernatural or otherwise. Often featuring the four original Ghostbusters—Venkman, Stantz, Spengler, and Zeddemore—or the recognizable 'No-Ghost' logo, the meme is used to signal a solution to a specific, often absurd, predicament. It captures a sense of 80s nostalgia while remaining a staple for humor involving teamwork, weird occurrences, and pop culture references.