The 'Even Speedwagon Is Afraid!' meme originates from the first arc of JoJo's Bizarre Adventure, Phantom Blood. During a battle against the antagonist Dio Brando, the narrator exclaims this iconic line to demonstrate the sheer power and intimidation of the villain, noting that even the seasoned street-thug-turned-ally Robert E. O. Speedwagon is paralyzed by fear. In internet culture, the meme is used as a hyperbolic reaction to signify that a situation, character, or event is genuinely frightening or overwhelming. It often appears in image macros where the top text describes a scenario and the bottom panel shows Speedwagon’s panicked expression, serving as the ultimate seal of 'this is serious business' within the anime community.