The 'Don't Lose Your Way' meme is derived from the iconic lyrics of the song 'Before My Body Is Dry,' which serves as the main theme for the protagonist Ryuko Matoi in the 2013 anime Kill la Kill. The meme gained traction because the song almost always plays during the most climactic and high-energy moments of the series, signaling a character's transformation or a sudden turnaround in a fight. Fans began using the phrase to accompany images of intense determination, sudden motivation, or any situation where a specific 'hype' song would realistically start playing. It has since become a staple of anime internet culture, used to parody dramatic reveals and celebrate the over-the-top nature of the original show's soundtrack.