The 'Do You Think God Stays in Heaven Because He too Lives in Fear of What He's Created' meme originates from the 2002 family film Spy Kids 2: The Island of Lost Dreams. Spoken by the character Romero, played by Steve Buscemi, the surprisingly existential line was intended to explain his isolation after his genetic experiments went wrong. However, the internet repurposed this heavy philosophical quote as the ultimate reaction to 'cursed' content, bizarre fan art, or unsettling technological developments like AI-generated monstrosities. It serves as a humorous way to suggest that humanity’s weirdest creations are enough to make even a deity hide away in terror.