The 'Dexter Can't Prove It' meme originates from the classic Cartoon Network series Dexter's Laboratory. The scene captures the child prodigy Dexter in a state of frustrated conviction, typically used to represent situations where someone is certain of a fact but lacks the tangible evidence to convince others. It gained popularity on social media platforms like Twitter and Reddit as a way to voice 'conspiracy theories' about everyday life, fandoms, or niche hobbies. The expressive animation of Dexter’s face makes it a versatile format for any 'I know I'm right' moment.