Originally released in early 2018, this clip comes from the CollegeHumor sketch titled 'Don't Eat Tide Pods' which satirized the viral and dangerous internet trend of the same name. The scene features Grant O'Brien as a frantic, rational friend attempting to convince Brennen Murphy’s character to stop consuming the colorful laundry detergent packets. Grant delivers the now-iconic, exasperated line, 'You gotta stop eating the Tide Pods!' while Brennen looks on with a glazed, unbothered expression. In meme culture, this clip serves as the ultimate 'voice of reason' reaction. It is commonly used to represent a person’s conscience, a concerned friend, or even a bank account trying to prevent someone from making a self-destructive or illogical decision. It perfectly captures the frustration of explaining why something obvious is a bad idea to someone who simply won't listen. Popular caption ideas include 'Me to my brain at 3 AM when I start thinking about embarrassing memories' and 'My bank account watching me buy my fourth iced coffee of the day.'