The 'Animation Nooooooo' meme is most famously derived from the climactic moment in 'Star Wars: Episode III – Revenge of the Sith' (2005). In this scene, the newly transformed Darth Vader, portrayed by Hayden Christensen and voiced by the legendary James Earl Jones, is informed by Emperor Palpatine that he killed Padmé in his anger. Upon hearing this, Vader breaks his restraints and bellows a long, agonized 'Nooooooo!' while the camera zooms out for dramatic effect. In meme culture, this clip is the gold standard for expressing hyperbolic despair, soul-crushing disappointment, or the realization of a catastrophic mistake. It is frequently used to mock one's own overreactions to minor daily inconveniences or to genuinely express grief over a lost game or a failed project. Example captions include: 'When you drop your phone and it lands face down on the concrete,' 'Me realizing the microwave was never plugged in,' or 'When you see your ex's new post.'